Amphetamines are addictive stimulants; consequently, the Vyvanse vs Adderall XR high provides users with a sense of euphoria which leads to addiction in the long run. Personal experiences: Adderall vs Vyvanse? No real high to speak of. Edit: Side questions, I've found to euphoria from Concerta to be quite enjoyable but frankly distracting in a way that might be best to avoid/minimise. How long does Adderall stay in your system (urine drug test)? Vyvanse/Lisdexamphetamine is the med I'm currently prescribed, and it feels like a real winner from here. Again, this is just my personal experience. So they’re both stimulants obviously but Vyvanse is reportedly not as hard on your cardiovascular system as Adderall is - Vyvanse is less jarring to your system and its effects are more leveled out and smoother than Adderall. Vyvanse gives off a more genuine social effect on my anxiety. In theory anyway. It's more like ~1:20 after dosing I look around and realize I'm medicated, versus starting to get anxious and energetic and knowing the onset is coming. MPH is like the strongest cup of coffee on the best/happiest day, without the shakes or the shits from too much caffeine. I can imagine the 'no kick in the ass' thing you said in regards to Vyvanse and I wonder if more people experience it that way or if they actually like that's it's a less intense but more longer-and-in-the-background kind off feeling. Because this happens gradually after ingestion peak plasms levels should not be as high as with pure Dextroamphetamine or Adderall. One study did look at the effect both drugs had on classroom-based behavior in a group of children with ADHD, and reported that both seemed equally effective at improving attention-span, rule following and interactions with peers and adults. Adderall rated 7.9/10 vs Vyvanse rated 7.5/10 in overall patient satisfaction. I've taken up to 110mg vyvanse before but I've never tried adderal. Both were well tolerated and no significant differences were noted in their side effects.3,4 -Vyvanse = LisDexamfetamine which is 100% dextroamphetamine that's coupled to the amino acid L-Lysin. Cochrane Database of Systematic Reviews 2011, Issue 6. Drugs.com, Anticipated Availability of First-Time Generics. Drugs.com, Vyvanse Prices, Coupons and Patient Assistance Programs. To be clear: I'm not asking about the pharmacology or science about both drugs, I am just curious to hear about peoples personal subjective experience with them. Revised 12/2015 Teva Select Brands, Vyvanse (lisdexamfetamine) [package insert]. I have taken slightly more than prescribed doses of Vyvanse, but at the end of the day, I always felt satisfied and slept like a baby. Mg for mg, vyvanse is significantly weaker, too; 20mg adderall is about 50mg vyvanse for stimulant equivalency purposes. please include whether or not the drug was prescribed to you (and if you don't mind: for which indication). Adderall XR Prices, Coupons and Patient Assistance Programs Drugs.com, Amphetamine/dextroamphetamine Prices, Coupons and Patient Assistance Programs. I still find it pretty useless when I take it now. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. I did a good amount of both through my high school and college years. Journal of Attention Disorders.2002;6(2):69‐75, Maneeton N, Maneeton B, Suttajit S et al. Dexerdrine should be talked about more, it’s just like vyvanse but works much faster and smoother. I know that's not necessarily the primary function of ADHD meds, and I might not really get it from any of them (even if they do help my focus), but I need that sense of productivity that I've always lacked. I’m now getting my prescriptions from a psychiatrist instead of from my gp and it probably goes without saying that my psychiatrist is infinitely more knowledgeable about these drugs, their mechanisms of action, and which specific drug/s tend to be more beneficial in treating specific disorders and their subtypes. If I take a 70mg Vyvanse, I can sleep the same night and I just feel alert. Very very clear when it was working and when it stopped working, like someone flipped a switch. And personal preference plays a role too - I know a lot of people can’t stand that amped up, jittery feeling that Adderall gives you. NOTE: I am not particularly interested in the science behind it, but rather in actual subjective experiences from people that have taken it! D amp is certainly better but I think the first effect I mentioned is much more significant. Exploratory meta-analysis on lisdexamfetamine versus placebo in adult ADHD. A lot of people claim to have euphoria from amphetamines but I guess their brain just works differently or maybe they've never done mdma or coke. I have to speculate that I must have been reacting negatively to that 25% l-isomer of amphetamine. Let me know if you have any other questions or if you need further clarification on anything. Medically reviewed by Drugs.com. I'm in the latter group. The dextroamphetamine is the one that is mainly responsible for it's actions on your cognition. But I know several people - my brother being one of them - who take Vyvanse and really like it & find it helpful. Dexedrine is kind of like Adderall light I guess you could say. Instead of declaring a war on drugs, we want to provide users and others who have an interest in the topic a place for serious and respectful discussion. Focalin vs Adderall: What's the difference? Adderall has more potential to be abused, mainly because it contains free amphetamine salts. Vyvanse doesn't have any real physical energy to speak of; it doesn't make me want to be up running around, just makes me want to be productive. Subscribe to Drugs.com newsletters for the latest medication news, alerts, new drug approvals and more. Mental Health Clinician 2014;4(1):8-10. Someone has linked to this thread from another place on reddit: [r/drugs] Personal experiences: Adderall vs Vyvanse? you probably wouldn't get much out of binge use. Expert Opin Pharmacother. It'll take same amount of time. Adderall has been around longer than Vyvanse. Vyvanse causes me to become very talkative, thoughtful and causes me to think much much deeper and just feels good, adderal causes me to feel an uncomfortable sense of speed (makes me feel too much like a tweaker honestly) and caused me too feel anger and negative emotions much quicker, nowhere near the same amount of euphoria from vyv. I have since taken vyvanse around 10 times, and have only taken adderal one other time due to it not being near as euphoric to me as the vyv. I’m so much more productive on Adderall than on Vyvanse but I’m a really laid back person so I think I need that kick in my ass to get me going. I still experience side effects to this day after years and years of constant daily use. This is a rate-limited process though which is why peak plasma concentrations of the active substance (dextroamphetamine) are only reached like 5-6 hours after ingestion. The raynauds stopped happening the day I switched from adderall to vyvanse; I'm guessing the PNS activity of levoamphetamine was to blame. I also feel it when it’s wearing off and I start to crash. Everything hits everyone differently. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. It doesn't build anxiety the way adderall can, and the onset and ramp down are much more gentle than adderall or methylphenidate. In the body the inactive prodrug get's metabolised and the L-Lysin amino accid get's seperated from the dextroamphetamine (this happens in red blood cells which means road of administration does not effect pharmacokineticcs much). Lisdexamfetamine is only available as Vyvanse, at a cost of $884 for 100 capsules ($8.84 per capsule).15 Don't hold your breath for a generic - one isn't expected until 2023!16, No. My doctor switched me from adderall xr to concerta because I said I wanted to try IR because if I take xr before work I pretty much don’t feel it by the time of my night class and he doesn’t want to prescribe IR for potential of abuse, so he said concerta should last longer. I also never feel a crash from it either though so I guess that’s one advantage. Weird i just found this post on google right when you commented. Weird, I thought. Just to be clear: I know Vyvanse is lisdexamphetamine and Adderall is 3:1 ratio dexamphetamine : levoamphetamine. They just get me "right". Attention-Deficit Hyperactivity Disorder (ADHD), Adderall (dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate) [package insert]. Risk of dependence (coming to rely on the drug) appears similar for both. Simon K, Worthy SL, Barnes MC, Tarbell B. Abuse-deterrent formulations: transitioning the pharmaceutical market to improve public health and safety. This is just my opinion/experience with it so I don’t know how helpful it’ll be for you. Cellphone games, organizing things that needn't be, etc. Interpretive Report. Now this was my GP prescribing it to me and I’ve never heard the “it takes a couple weeks for you to notice it’s working” thing from anyone else ever. Shoot me a pm. Although I'm familiair with the reasoning behind it and how it works, I am very curious to hear from some people that tried both to hear if they actually experience it that way / differently. Even though they are medications for ADHD, people often misuse these drugs for leisure such as drinking on Adderall. The other side effects that I experience with Adderall include: feeling shaky/jittery at times, constantly clenching/grinding my teeth which makes my jaw really sore so I chew gum to help with that, severe dry mouth, having no appetite at all which sucks when your blood sugar drops and there’s not a single thing in the world you want to eat and anything you do manage to force down tastes like cardboard, occasional muscle cramps that are pretty brutal for about a minute or so (I get them in my feet/toes while my rm gets them in his hands), overall increased body aches and pains (I think from keeping your muscles tensed up too long), headaches occasionally, and feeling pretty sad, depressed, anxious, and cranky during the crash phase. Uploaded 09/2006. If I take 40mg of Adderall, I'm not going to sleep for two days and have a really positive speedy high. I don’t know anyone that just takes Vyvanse by itself. By blocking their re-uptake, levels of these neurotransmitters between nerves are increased, which helps relieve symptoms of inattention and agitation in children and adults with ADHD.1, Unfortunately, researchers have not really looked into how effective Adderall is compared to Vyvanse, and vice-versa.

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