As with the previous diabetes studies, oral alpha-lipoic acid supplements were generally less effective or had no effect at all. It's most often used to help with diabetic neuropathy, which is a condition where you lose feeling in areas of your body as a complication of diabetes, like numbness, tingling, and burning pains in your legs and feet. Alpha-lipoic acid's ability to enhance calorie burning and promote weight loss has been exaggerated by many diet gurus and supplements manufacturers. Alpha-lipoic acid can also recycle "used" antioxidants, including vitamin C, vitamin E, and a potent amino acid compound known as glutathione. Whenever these antioxidants neutralize a free radical, they destabilize and become free radicals themselves. The remaining cases are of unknown origin. Alpha-lipoic acid is also considered an antioxidant, meaning that it can neutralize harmful compounds called free radicals that damage cells at the genetic level.. Oral alpha-lipoic acid to prevent chemotherapy-induced peripheral neuropathy: a randomized, double-blind, placebo-controlled trial. It occurs in all cells, and plays a role in the metabolism of glucose. What makes alpha-lipoic acid so unique is that it is soluble in both water and fat. In addition to supplements, alpha-lipoic acid is synthesized in the body and found in many of the foods we eat, especially Brussels sprouts, spinach, broccoli, peas, brewer's yeast, potato, yams, carrots, rice bran, and organ meats. Effects of dietary L-carnosine and alpha-lipoic acid on growth oerformance, blood thyroid hormones and lipid profiles in finishing pigs. By contrast, there is no evidence that the supplement can prevent or treat type 1 diabetes, the form of the disease typically associated with an immune system malfunction. Alpha lipoic acid (ALA) is a fat-soluble, sulfur-containing, vitamin-like antioxidant. It is believed by some that alpha-lipoic acid, given in large enough doses, can counter this stress by exerting potent antioxidant activity. DiPardo retired from drug discovery research in 2009 and, since 2010, has covered fitness and well-being for various online publications. Understanding the Benefits of Cissus Quadrangularis. 2011;124(1):85.e1-8. The effects of alpha-lipoic acid supplementation on glucose control and lipid profiles among patients with metabolic diseases: A systematic review and meta-analysis of randomized controlled trials. // Leaf Group Lifestyle. The aim of the study was to test three antioxidants — alpha lipoic acid, metformin, and glimepiride. Asian-Australas J Anim Sci. To ward off chronic, age-related diseases to that effect is made mitochondria. Blood glucose Levels, { { form.email } }, for signing up raw materials it needs make... 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