Round red blood cells can move easily through the blood vessels but sickled shaped cells interconnect and can result in blood clots. Sickle cell anemia is a hereditary disorder that mostly affects people of African ancestry, but also occurs in other ethnic groups, including people who are of Mediterranean and Middle Eastern descent. Sickle cell anemia is more common in certain ethnic groups including: People of African descent, including African Americans, Hispanic-Americans from Central and south America, People of Middle Eastern, Asian, Indian, and Mediterranean descent. Sickle Cell Anemia is actually more common in people who have a history of living in malaria ridden areas such as South Africa. This explains why the gene for sickle cell anemia is found in about 7% of the population in malaria-stricken regions, but is virtually nonexistent elsewhere. These likely areas are why African Americans are more prone to have sickle cell disease. Sickle cell disease (SCD), or sickle cell anaemia, is a major genetic disease that affects most countries in the African Region. It is more common for people of African descent to get sickle cell anemia. For example, a genetic variance causing sickle cell anemia actually protects against another disease, malaria. Sickle cell trait (HbAS) associates with impaired urinary concentration, hematuria, and renal papillary necrosis, but its prevalence among African Americans with ESRD is unknown. The red blood cells change shape in order to pierce the malaria germ which kills it. 1 in _____ African Americans carries a sickle cell … More than 70,000 Americans have sickle cell anemia. We performed a cross-sectional study reviewing available hemoglobin phenotypes for 188 of 206 adult African-American pati … In sickle cell disease, the normal round shape of red blood cells become like crescent moons. However, it is worth mentioning that there is a significant difference in the occurrence of sickle cell in Africans versus African Americans. The map above shows a … There are many genes that influence just this. Actually, white people who live in Malaria ridden area's also have sickle cells. It is more common for people of African descent to get sickle cell anemia. However, SCD is predominantly common among people with specific descent that includes African, Turkish, Greeks, Italian, Cuban, Latin Americans, Indian nationals, and Arabs to name a few.

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